Keating Lab

About the Lab

Welcome to the Keating Lab! We are a research group dedicated to advancing the field of transplantation medicine through multiomic science. Our work delves deep into the intricate molecular mechanisms of genomics, transcriptomics, proteomics, metabolomics and integrating these powerful datasets to understand the biology of transplant biology through different molecular lenses. By integrating advanced immunology with insights from molecular pathology and the innovative application of artificial intelligence (AI), we aim to decipher the molecular underpinnings of transplant outcomes, ultimately striving to enhance patient outcomes and usher in a new era of personalized, precision medicine.

Lab News

• Francesca Zanoni presents "Genetic Determinants of Kidney Transplant Outcomes: A Large-Scale Multi-Ancestry GWAS Meta-Analysis" at the World Transplant Congress, August 2025.
• Kiana Moi will present "Comprehensive Long-Read Whole Genome Sequencing in 7 Human Xenotransplant Recipients" at the WTC 2025.
• Mercy Rophina will present "Urinary Single-Cell RNA Sequencing from a Pig Kidney to Living Human Xenotransplantation Reveals Dynamic Cellular Changes" at the WTC 2025.
• Qian Guo will present "Longitudinal Multi-Omics Profiling Reveals Molecular Responses in a Living Human Receiving a Gene-Edited Pig Kidney Xenograft" at the WTC 2025.
• Qian Guo will present "Large Scale Urinary Metabolomic Screening in the Prospective Multicenter VIRTUUS Children's Study" at the WTC 2025.
• Shreyas Joshi will present "Longitudinal Analysis of Immune Responses in Porcine Kidney Transplant Recipients" (poster) at the WTC 2025.
• Brendan Keating will present "Genetic and Other Recipient Factors Impacting Success in Transplantation" at the WTC 2025.
• Brendan Keating will present "NK Cells in Human Decedent Model" at the WTC 2025.